Kimya Bölümü

Bu koleksiyon için kalıcı URI

http://hdl.handle.net/11527/25345

Gözat

Yazar "Coşkun, İbrahim Yağız" ile Kimya Bölümü'a göz atma
  • Öge
    Investigation of advanced biological properties of carbon, carbon-boron quantum dots, and copper (II) phthalocyanine nanoconjugates
    (Wiley, 2024) Özçeşmeci, Mukaddes ; Gümrükçü, Selin ; Ünlü, Caner ; Coşkun, İbrahim Yağız ; Özdemir, Sadin ; Yalçın, M. Serkan ; Tollu, Gülşah ; Özçeşmeci, İbrahim ; orcid.org/0000-0002-6723-6902 ; orcid.org/0000-0002-3135-6590 ; orcid.org/0000-0002-0612-3111 ; orcid.org/0000-0002-8723-383X ; Kimya Bölümü
    Non-peripherally, glycerol terminal groups substituted copper (II) phthalocyanine were non-covalently (electrostatic and/or π–π interaction) attached to carbon (CQD) and carbon-boron quantum dots (CBQD) to form QDs-Pc nanoconjugate systems. Synthesized novel phthalocyanine compounds and QDs-Pc conjugate systems were characterized using different spectroscopic techniques. Various biological assessments were applied to newly synthesized compounds. Conjugates 4 and 5 had a maximal free radical scavenging activity of 71.3% and 68.1% at a 100 mg/L concentration. Compounds exhibited high antidiabetic activities at 200 mg/L. Also, compounds showed significant DNA nuclease activity at all tested concentrations. The most efficient MIC value was obtained as 4 mg/L against Enterococcus hirae and Enterococcus feacalis. This MIC value was further decreased after photodynamic therapy, and it was observed that the antimicrobial effects of the compounds increased. Inhibition of microbial cell viability was obtained as 100% for all compounds. In addition, compounds exerted perfect biofilm inhibitory effects.
  • Öge
    Modulating spectral response of raw photosynthetic pigments via ternary cadmium chalcogenide quantum dots : simultaneous enhancement at green spectrum and inhibition at UV region
    (Springer, 2024) Aykut, Sümeyye ; Ük, Nida ; Coşkun, İbrahim Yağız ; Şahin Keskin, Sultan ; Nar, Ilgın ; Trabzon, Levent ; Ünlü, Caner ; 0000-0001-7544-5360 ; 0000-0001-6626-8665 ; 0000-0002-1666-7438 ; 0000-0001-6606-5622 ; 0000-0003-2300-3071 ; 0000-0002-7323-3943 ; 0000-0002-0612-3111 ; Kimya Bölümü
    Photosynthesis relies on the absorption of sunlight by photosynthetic pigments (PPs) such as chlorophylls and carotenoids. While these pigments are outstanding at harvesting light, their natural structure restricts their ability to harvest light at specific wavelengths. In this study, Oleic acid-capped CdSeS and CdTeS ternary quantum dots (QDs) were synthesized using a novel two-phase synthesis method. Then, these QDs were used to interact with raw PPs, a mixture of chlorophylls and carotenoids isolated from spinach. Our findings revealed the following: (1) Interacting QDs with raw PPs effectively inhibited the chlorophyll fluorescence of the pigments upon excitation in UV light region (250–400 nm) without causing any damage to their structure. (2) By forming an interaction with QDs, the chlorophyll fluorescence of raw PPs could be induced through excitation with green-light spectrum. (3) The composition of the QDs played a fundamental role in their interaction with PPs. Our study demonstrated that the photophysical properties of isolated PPs could be modified by using cadmium-based QDs by preserving the structure of the pigments themselves.