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Preparation and evaluation of cerium oxide-bovine hydroxyapatite composites for biomedical engineering applications

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Gökçe, Hasan
Dr.

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Elsevier BV

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Abstract

The fabrication and characterization of bovine hydroxyapatite (BHA) and cerium oxide (CeO2) composites are presented. CeO2 (at varying concentrations 1, 5 and 10wt%) were added to calcinated BHA powder. The resulting mixtures were shaped into green cylindrical samples by powder pressing (350MPa) followed by sintering in air (1000-1300°C for 4h). Density, Vickers microhardness (HV), compression strength, scanning electron microscopy (SEM) and X-ray diffraction (XRD) studies were performed on the products. The sintering behavior, microstructural characteristics and mechanical properties were evaluated. Differences in the sintering temperature (for 1wt% CeO2 composites) between 1200 and 1300°C, show a 3.3% increase in the microhardness (564 and 582.75HV, respectively). Composites prepared at 1300°C demonstrate the greatest compression strength with comparable results for 5 and 10wt% CeO2 content (106 and 107MPa) which are significantly better than those for 1wt% and those that do not include any CeO2 (90 and below 60MPa, respectively). The results obtained suggest optimal parameters to be used in preparation of BHA and CeO2 composites, while also highlighting the potential of such materials in several biomedical engineering applications.

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Journal of the Mechanical Behavior of Biomedical Materials

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1751-6161

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OPEN

Keywords

Ceramics, Compressive Strength, diffraction, Mechanical properties, Fabrication and characterizations, Biocompatible Materials, powder, pressure, Sintering, biomedical engineering, Materials Testing, animal, Microstructure, cerium oxide, Mammals, biomaterial, article, Temperature, hydroxyapatite, Oxides, Cerium, particle size, composite material, compressive strength, Animals, Biocompatible Materials/*chemistry, Biomedical Engineering, Bone Substitutes/*chemistry, Cattle, Ceramics, Cerium/*chemistry, Compressive Strength, Durapatite/*chemistry, Hardness, Materials Testing, Microscopy, Electron, Scanning, Powders, Pressure, Stress, Mechanical, Temperature, unclassified drug, cerium, Hydroxyapatite composite, priority journal, Applications, bovine hydroxyapatite, Powders, Biomedical engineering, Scanning electron microscopy, Vickers microhardness, scanning electron microscopy, Micro-structural characteristics, Cerium oxides, physical sciences, X ray diffraction, Biomedical Engineering, Compressive strength, ceramics, microtechnology, chemistry, Bovinae, Hydroxyapatite, Hardness, Compression strength, Pressure, Animals, materials testing, concentration (parameters), natural sciences, mechanical stress, Bioceramics, temperature, engineering and technology, Cerium oxide, Sintering temperatures, Engineering applications, ceric oxide, hardness, Durapatite, nano-technology, Microhardness, Bone Substitutes, Microscopy, Electron, Scanning, Bovine hydroxyapatite, Cattle, Stress, Mechanical, bone prosthesis

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