Design and Fabrication of Integrated Microchannel and Peristaltic Micropump System for Inertial Particle Separation

Abstract

In particle separation applications, conventional syringe pumps are widely used to supply fluid flow into microchannels at a controlled flow rate. However, their bulky structures lack the development of compact particle separation systems which is essential for all LoC (Lab on a Chip) systems. In this study, we designed and fabricated a peristaltic micropump which can be integrated into an inertial particle separation microchannel at the same layer with a compact design. Since inertial particle separation can be done without a need for an external force field, we aimed to develop a μTAS (Micro Total Analysis Systems) system which is able to realize particle separation in an integrated micropump-microchannel system. The circular micropump channel made of two PDMS layers and its width is optimized. The 3D-Printed micropump is actuated by a stepper motor, and the rate of pumped fluid is monitored by an LCD screen connected and programmed to system according to the system parameters. Micropump has a theoretical capacity of supplying particle carrying fluid at the flow rate of 25.47 ml/min when the stepper motor is rotated at 330 rpm.