Effects of using depletion interaction theory in variable hematocrit levels of bio-flows

Abstract

In our study, hematocrit levels and differences in rheological properties of blood, especially in red blood cell (RBC) using depletion interaction theory are investigated. In simulation, we apply depletion interaction theory which is a chemical concept at mesoscale level and unite with bio-fluid mechanics at a macro scale level. In order to differentiate the advantages of this theory, two-phase simulations are performed and RBC aggregation is studied. Wall shear stresses (WSS), phase distributions and volume fractions, with a range of hematocrit levels of RBC are calculated using depletion theory for multi-phase simulation and compared with numerical and experimental data in literature.In our study, hematocrit levels and differences in rheological properties of blood, especially in red blood cell (RBC) using depletion interaction theory are investigated. In simulation, we apply depletion interaction theory which is a chemical concept at mesoscale level and unite with bio-fluid mechanics at a macro scale level. In order to differentiate the advantages of this theory, two-phase simulations are performed and RBC aggregation is studied. Wall shear stresses (WSS), phase distributions and volume fractions, with a range of hematocrit levels of RBC are calculated using depletion theory for multi-phase simulation and compared with numerical and experimental data in literature.