LEE- Bilgisayar Mühendisliği Lisansüstü Programı
Bu topluluk için Kalıcı Uri
Gözat
Konu "Digital image processing" ile LEE- Bilgisayar Mühendisliği Lisansüstü Programı'a göz atma
Sayfa başına sonuç
Sıralama Seçenekleri
-
ÖgeClassification of melanoma malignancy in dermatology(Lisansüstü Eğitim Enstitüsü, 2021) Gazioğlu, Bilge Süheyla ; Kamaşak, Mustafa Ersel ; 709938 ; Bilgisayar MühendisliğiCancer has become one of the most common diseases all over the world in recent years. Approximately 40% of all incidences is skin cancer. The frequency of sightings of skin cancer has increased by 10 times in the last 50 years, and the risk of developing skin cancer is about 20%. Skin cancer has symptoms such as abnormal tissue growth, redness, pigmentation abnormalities and nonhealing wounds. Melanoma is a rare type of skin cancer with higher mortality compared to other types of skin cancers. Melanoma can be defined as a result of uncontrolled division and proliferation of melanocytes. Worldwide, melanoma is the 20th most common cancer and there are an estimated 287,723 new cases (1.6% of all cancers). In USA, more than two hundred thousand new cases of melanoma were diagnosed in 2021 and it increases more rapidly than other forms of cancer. Melanoma incidence increased up to 237% in the last 30 years. In our country, Turkey, melanoma is relatively rare compared to the other countries. Cancer cells display a rapid grow and systematic spread. As in all types of cancer, early diagnosis is of great importance for the treatment of skin cancer. Early diagnosis improves treatment success and prognosis. To detect a melanoma, changes in color, shape and structure of the skin, swelling and stains on the skin are carefully examined by the physicians. Besides the physician investigation, computer aided diagnosis (CAD) mechanisms are recommended for early diagnosis. In this thesis, deep learning models have been used to determine whether skin lesions are benign or malignant melanoma. The classification of the lesions is considered from two different points of view. In the first study, effect of objects in the image and image quality on classification performance was examined by using four different deep learning models. In addition, sensitivity of these models was tested. In the second study, it was aimed to establish a pre-diagnosis system that could help dermatologists by proposing a binary classification (benign nevi or malignant melanoma) mechanism on the ISIC dataset. In clinical settings, it is not always possible to capture flawless skin images. Sometimes skin images can be blurry, noisy, or have low-contrast. In other cases, images can have external objects. The aim of the first study is to investigate the effects of external objects (ruler, hair) and image quality (blur, noise, contrast) using widely used Convolutional Neural Networks (CNN) models. Classification performance of frequently used ResNet50, DenseNet121, VGG16 and AlexNet models are compared. Resilience of the mentioned models against external objects and image quality was examined. Distortions in the images are discussed under three main headings: Blur, noise and contrast changes. For this purpose, different levels of image distortions were obtained by adjusting different parameters. Data sets were created for three different distortion types and distortion levels. Firstly, the most common external object in skin images is hair on skin. In addition, rulers are commonly used as a scale for suspicious lesions on skin. In order to determine the effect of external objects on lesion classification, three separate test sets were created. These sets consist of images containing a ruler, hair and no external object (none). The third dataset consists only of mole (lesion) images. With the three datasets, four models were trained and their classification performances were analyzed. In fact, the best result was expected to be classified with a higher accuracy of the dataset that did not contain any object except the lesion. However, when the results are analyzed, since the image set containing hair had the highest number of images in the total dataset, the best classification performance in our system was measured by using DenseNet model on this subset. As a result of these tests, ResNet model showed a better classification performance compared to other models. Melanoma images can be better recognized under contrast changes unlike the benign images, we recommend ResNet model whenever there is low contrast. Noise significantly degrades the performance on melanoma images and the recognition rates decrease faster compared to benign lesions in noisy set. Both classes are sensitive to blur changes. Best accuracy is obtained with DenseNet model in blurred and noisy datasets. The images contain ruler has decreased the accuracy and ResNet has better performance in this set. Hairy images have the best success rate in our system since it has the maximum number of images in total dataset. We evaluated the accuracy as 89.22% for hair set, 86% for ruler set and 88.81% for none set. We can infer that DenseNet can be used for melanoma classification with image distortions and degradations. As a general result of the first study, we can conclude that DenseNet can be used for melanoma classification since it is more resistant to image distortion. In recent years, deep learning models with high accuracy values in computer aided diagnosis systems have been used frequently in biomedical image processing research area. Convolutional neural networks are also widely used in skin lesion classification to increase classification accuracy. In another study discussed in this thesis, five deep learning models were discussed in order to classify the images in the specially created skin lesions dataset. The dataset used in this study consists of images from ISIC dataset. In the dataset which is available in 2020, there are two classes of benign and malignant and three diagnosis consist of nevus, melanoma and unknown. We only considered images with nevus and melanoma diagnosis. Dataset had 565 melanoma and 600 benign lesion images in total. We separated the 115 images for the class of malignant melanoma and 120 images for the benign nevi class as our test set. The rest of the data was used for model training. With pre-processing methods such as flipping and rotation, the training dataset has divided into 5 parts and the number of images in the train set was increased. DenseNet121, DenseNet161, DenseNet169, DenseNet201, ResNet18, ResNet50, VGGNet19, VGGNet16_bn, SqueezeNet1_1, SqueezeNet1_0 and AlexNet models were trained with each subset. Using these models an ensemble system was designed. In this system, results the models were combined with the majority voting method. The accuracy of the proposed model is 95.76 % over the data set.